Dual index grade sequence pattern recognition of extracts with ethanol of Mingmu Dihuang pills and Zhibai Dihuang pills / 中国中药杂志

<p><b>OBJECTIVE</b>A new pattern recognition method suitable for traditional Chinese patent medicine was established in this paper, which is named as the Dual index grade sequence pattern recognition.</p><p><b>METHOD</b>In this method the quality gradation was defined mathematically relying on normal distribution. By this way samples can be clustered and classified depending on which quality gradation is wanted, and the grading samples quantitatively relative to quality can be performed simultaneously. Especially, the redundant information with respect to pattern recognition hiding in dual index sequences of samples can be removed effectively by applying the good grade sequences, which make the pattern recognition results accurate excellently. This approach possesses the advantages of both supervised classification and unsupervised cluster methods. Samples can be clustered and classified at the same time without any standard samples, and the operation is accomplished based on the good grade similar sequences themselves being as the classifying marks. Moreover, the subclasses in each class can be identified more subtly.</p><p><b>RESULT</b>The infrared fingerprint spectra of extracts of 27 kinds of Mingmu Dihuangwan pills and Zhibo Dihuangwan pills samples extracted with ethanol were analyzed with the method proposed in this paper. The results showed that these pills can be classified in their subclasses clearly, respectively.</p><p><b>CONCLUSION</b>The Dual index grade sequence pattern recognition is a new and effective one for identifying complex biological products made from complex herbal medicines.</p>

Dissolution and differentiation of phytochemical components from mixture of Radix Paeoiae Alba and Radix Glycyrrhizae with different ratios / 中国中药杂志

<p><b>OBJECTIVE</b>To investigate dissolution properties among different components with various polarities and to distinguish these groups from each other.</p><p><b>METHOD</b>Ultraviolet fingerprint spectra (UV FPS) of the components from Baishao (Radix Paeoiae Alba) and Gancao (Radix Glycyrrhizae) with various proportions, extracted with chloroform, ethanol and water successively, were obtained. The analysis was performed on the absolute and relative absorptions of peaks in UV FPS.</p><p><b>RESULT</b>Dissolutions in different rates and in synergy among chemical components were observed, by which different components can be distinguished.</p><p><b>CONCLUSION</b>Dissolution kinetics and processes of the various chemical components from medicinal herbs are of great difference.</p>

Dual-index sequence analytical method for IR fingerprint spectra of the chloroform extract of Radix Glycyrrhizae / 中国中药杂志

<p><b>OBJECTIVE</b>To investigate a new method for the analysis of IR fingerprint spectra of Radix Glycyrrhizae.</p><p><b>METHOD</b>Two indexes, common peak ratio and variation peak ratio, are used to compare the IR spectra of various Radix Glycyrrhizae samples, and the values are calculated by means of sequent analysis.</p><p><b>RESULT AND CONCLUSION</b>The dual-index sequence method provides a good approach to discriminate Radix Glycyrrhizae samples of different species and geographical origins.</p>